The Efficacy and Mechanism Evaluation (EME) Programme is funded by the Medical Research Council (MRC) and managed by the National Institute for Health Research (NIHR), as the lead organisation for evaluation, trials and studies under coordinated MRC-NIHR strategy for translational research.

The EME programme supports excellent clinical trials and other studies to enhance the translation of basic into applied research, with an ultimate view to improving patient health or care. It is interested in studies which evaluate the clinical efficacy of an intervention (where proof of concept in humans has already been achieved); and those which may in addition add significantly to our understanding of biological or behavioural mechanisms and processes.

Preliminary applications for research can be made on an ongoing basis, however there are three submission deadlines each year. In order for a proposal to be considered in the next assessment round, it must reach the EME offices by 1pm on Monday 21 March 2011.

For more information visit the EME website

If you have any queries please email info@eme.ac.uk or telephone on 02380 594 303.